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Noboru Otsuka Selected Research

Flurbiprofen (Froben)

1/2018[Pharmacological action and clinical outcome of newly developed NSAIDs patch, "LOQOA® tape"].
12/2017A minimal impact of long-term S-flurbiprofen plaster application on kidney function in osteoarthritis patients.
1/2017The efficacy and safety of S-flurbiprofen plaster in the treatment of knee osteoarthritis: a phase II, randomized, double-blind, placebo-controlled, dose-finding study.
1/2017Efficacy of S-flurbiprofen plaster in knee osteoarthritis treatment: Results from a phase III, randomized, active-controlled, adequate, and well-controlled trial.
8/2016The Long-Term Safety of S-Flurbiprofen Plaster for Osteoarthritis Patients: An Open-Label, 52-Week Study.
2/2016Analgesic Effect of the Newly Developed S(+)-Flurbiprofen Plaster on Inflammatory Pain in a Rat Adjuvant-Induced Arthritis Model.
1/2016Topical Anti-Inflammatory and Analgesic Effects of Multiple Applications of S(+)-Flurbiprofen Plaster (SFPP) in a Rat Adjuvant-Induced Arthritis Model.

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Noboru Otsuka Research Topics

Disease

3Knee Osteoarthritis
01/2018 - 01/2017
3Pain (Aches)
01/2018 - 01/2016
3Osteoarthritis
12/2017 - 01/2016
2Musculoskeletal Diseases (Musculoskeletal Disease)
01/2018 - 01/2017
2Arthritis (Polyarthritis)
02/2016 - 01/2016
2Ureteral Obstruction
04/2008 - 12/2006
1Kidney Diseases (Kidney Disease)
12/2017
1Dermatitis
08/2016
1Hyperalgesia
02/2016
1Edema (Dropsy)
01/2016
1AIDS-Related Complex (ARC)
09/2009

Drug/Important Bio-Agent (IBA)

7Flurbiprofen (Froben)FDA LinkGeneric
01/2018 - 01/2016
4Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
01/2018 - 01/2016
4Pharmaceutical PreparationsIBA
12/2017 - 01/2016
2spleen fibrinolytic proteinase (human) (SFP)IBA
01/2018 - 02/2016
2Analgesics (Analgesic Drugs)IBA
02/2016 - 01/2016
2L-xylulose reductaseIBA
04/2008 - 12/2006
1CreatinineIBA
12/2017
1NitrogenIBA
12/2017
1Urea (Carbamide)FDA LinkGeneric
12/2017
1Dinoprostone (PGE2)FDA Link
02/2016
1Ketoprofen (Orudis)FDA LinkGeneric
02/2016
1loxoprofen (CS 600)IBA
02/2016
1salicylhydroxamic acid (SHAM)IBA
09/2009
1Proteins (Proteins, Gene)FDA Link
09/2009
1Pyruvaldehyde (Methylglyoxal)IBA
04/2008
1Glyoxal (Ethanedial)IBA
04/2008
13-deoxyglucosoneIBA
04/2008

Therapy/Procedure

1Knee Replacement Arthroplasty (Total Knee Replacement)
01/2016